# Tumor Suppressor Gene --- A **tumor suppresor gene** is a [[gene]] that [[cell cycle regulation|regulates the cell cycle]]. If they sense that something is wrong, they can trigger [[cancer|apoptosis]], or slow the [[cell cycle]] until whatever's wrong can be fixed. These types of genes are often found damaged in cancers. ## Types There are three **types** of tumor supressors: ### Caretaker Genes ### Gatekeeper Genes ### Landscaper Genes ## Notible Examples [[cell cycle regulation#Rb E2F|Rb]] and [[cell cycle regulation#P53 P21|P53]] ## Contrasted With [[oncogenes]] ___